UMass Neurosciences Publications – April 2024

This month’s featured researcher is Karine Fenelon. Karine is an Assistant Professor in the Department of Biology. Read a wonderful profile about her life’s journey in the Stories of Women in Neuroscience. Her lab investigates the neural circuitry that underlies sensory gating. They recented publised a paper in the journal Brain Research titled, “Deciphering the role of brainstem glycinergic neurons during startle and prepulse inhibition“. This paper, which was the PhD dissertation work of NSB student, Wanyun Huang, shows the contribution of glutamatergic and glycinergic neurons to acoustic startle responses. Karine will be one the featured speakers in the Interdisciplinary Neurosciences Conference on May 30th.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in April. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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UMass Neurosciences Publications – February 2024

This month’s featured researcher is Dr. Courtney Babbitt. Courtney is an Associate Professor in the Biology Department. Her lab studies gene regulation with a particular focus on primate brain evolution. She has two publications already this year, one in the journal eLife, titled, “Tempo and mode of gene expression evolution in the brain across primates“, shows variations in gene expression in humans and chimps that correlate with brain size. The other paper, published in Genome Biology and Evolution, shows that human and chimp astrocytes have contributed greatly to glucose metabolism in humans.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in February. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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UMass Neurosciences Publications – November 2023

This month’s featured researcher is Dr. Alissa A. Nolden, who is an Assistant Professor and holds the Clydesdale Professorship in the Department of Food Science. Her lab studies chemosensory perception in humans. In particular they examine how individual differences in responses to foods and chemicals is associated with genetic variability, and how chemosensory perception changes as a result of dietary exposure, disease or therapeutic compounds. She was recently an author on a paper in the Journal of Voice titled, “Examining the Influence of Chemosensation on Laryngeal Health and Disorders“. She has examined taste loss in cancer patients. She was recently quoted in Science Magazine regarding a study that examined why the COVID-19 remedy paxlovid makes things taste bitter.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in November. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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UMass Neurosciences Publications – October 2023

Meghan Huber

This month’s featured research is Dr. Meghan Huber. Meghan is an Assistant Professor in the Department of Mechanical and Industrial Engineering in the College of Engineering. She also has adjunct appointments in the Department of Biomedical Engineering, and the Manning College of Information and Computer Sciences. Meghan runs the Human Robot Systems Laboratory, which focuses on understanding how humans and robots can learn from the physical interactions of one another. She has a recent paper in the Journal of Neurophysiology, which examines energy expenditures during human walking by simulating responses on a split treadmill. She applies some of this knowledge to wearable exoskeletons as described in a recent BioRxiv preprint.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in October. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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Postdoc Spotlight: Des Ramirez

This month’s Postdoc Spotlight is honoring Dr. M. Desmond Ramirez. Des has been a Postdoctoral Research Associate in the Katz Lab, but will be heading to the Pacific Northwest to join Cris Neill’s lab studying the octopus visual system. Des has a passion for vision; he completed his PhD at the University of California Santa Barbara studying octopus “skin sight” and he earned his MS at Michigan State where he studied the role of vision in the honeybee dance language. During his time in the Katz Lab, Des created a single cell transcriptomic atlas of neurons in the nudibranch Berghia stephanieae. His work is available in BioRxiv and awaiting review elsewhere.

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Student Spotlight – Phoenix Quinlan

Phoenix Quinlan

This month’s student spotlight is on Phoenix Quinlan, who is a PhD student in the Neuroscience & Behavior Graduate program. She is in Paul Katz’s lab in the Biology Department. Phoenix was recently spotlighted as an Early Career Researcher by the Journal of Experimental Biology for a paper that she published in that journal titled, State-dependent, visually guided behaviors in the nudibranch Berghia stephanieae, which shows that despite their simple eyes, nudibranchs can use visual cues for navigation. The Katz lab recently received a grant from NIH in collaboration with a lab at Harvard to study how newly born neurons are incorporated into neural circuits in the brain of this mollusc.

UMass Neurosciences Publications – September 2023

This month’s featured researcher is Sunghoon Ivan Lee, who is an Associate Professor in the Manning College of Information and Computer Sciences. His lab develops novel digital sensors that can help with personal health monitoring and was recently awarded a large NIH grant to develop a way of tracking body movements as way to help with stroke survivors’ rehabilitation. Ivan is an author on a recent paper in the Journal of Neurology titled, Estimation of ataxia severity in children with ataxia-telangiectasia using ankle-worn sensors. He will also be the speaker on October 25th for Neuroscience and Behavior Seminar series.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in September. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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UMass Neurosciences Publications – Summer 2023

ChangHui Pak

This summer’s featured Researcher in Dr. ChangHui Pak, who is an Assistant Professor in the Department of Biochemistry and Molecular Biology. She has joined UMass in 2018 after completing postdoctoral research in the lab of Nobel laureate, Thomas Sudhof. The Pak Lab studies the molecular signaling pathways involved in synapse formation. One of the techniques that they use is the creation of brain organoids from induced Pluripotent Stem Cells (iPSCs). She was recently senior author on a Book Chapter titled, “Method to Generate Dorsal Forebrain Brain Organoids from Human Pluripotent Stem Cells” published in Stem Cell-Based Neural Model Systems for Brain Disorders.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online from May to August. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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UMass Neurosciences Publications – April 2023

Alexander Surovov

This month’s featured researcher is Alexander Suvorov, who is an Associate Professor of Environmental Health Sciences and the Graduate Program Director of Environmental Health Sciences in the School of Public Health and Health Sciences. Alexander is also an associate member of the Neuroscience & Behavior Graduate program. His lab studies environmental endocrine disruptors that have the ability to interfere with endogenous hormonal signaling. Exposure to these substances during critical periods of prenatal or neonatal life may cause permanent reprogramming of target tissues, likely epigenetic in nature, which often do not present immediate phenotypes but can ultimately lead to adulthood onset diseases. He is a co-author on a review article that appeared recently in Human Reproduction Update titled, “Age-associated epigenetic changes in mammalian sperm: implications for offspring health and development“. This work dovetails with a recent NSB seminar by Bianca Marlin on transgenerational transmission of information. It also resonates with the theme of the Neuroscience of Aging for the May 3st Interdisciplinary Neurosciences Conference

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in April. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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Student Spotlight – Hui Wei

Hui Wei is a third-year Computer Science PhD student in the Manning College of Information and Computer Sciences, where he works under supervision of Prof. Benjamin Marlin in the Robust and Efficient Machine Learning (REML) lab. His research interest is applying machine learning to improving human health. Currently, he is working on machine learning for mobile health and the missing value problem in the time series data. Previously, Hui was working on evaluating the clinical diagnostic accuracy of dementia subtypes, with Prof. Narges Razavian in the Department of Population Health, NYU Grossman School of Medicine.

His recent publication in Frontiers in Aging Neuroscience compares the diagnosis in the clinic with autopsy results on Alzheimer’s disease, Lewy body disease and their combination with respect to different Clinical Dementia Rating stages. They demonstrate the diagnosis of these dementia subtypes is inaccurate and also suffers from the significant disparity in race and sex.

UMass Neurosciences Publications – March 2023

Lucy Xiaolu Wang

This month’s featured researcher is Dr. Lucy Xiaolu Wang. Lucy is an Assistant Professor in the Department of Resource Economics in the College of Social and Behavioral Sciences. She is also a Faculty Research Fellow at the Max Planck Institute for Innovation and Competition in Germany and a Faculty Associate at the Canadian Centre for Health Economics. In March, she and a collaborator published an article in The Conversation, describing her economic analysis published in PLoSOne of the Human Brain Project (HBP), a controversial $1.3 billlion European initiative that was originally led by Henry Markham. They examined the user interactions on the HBP public-access online forum to determine the value of online collaborative platforms.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in March. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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Undergraduate Student Spotlight – Yesha Patel

Yesha Patel is a senior Biochemistry & Molecular Biology and Economics dual degree undergraduate student as well as a member of the Commonwealth Honors College at the University of Massachusetts Amherst. On campus, Yesha has been a TA in the Biology department for the last two years and is in the Minutemen Equity Fund. Since she was a sophomore, Yesha has been working summers in Dr. Ella Zeldich’s lab at Boston University’s School of Medicine. She is an author on a paper that was recently published in the International Journal of Molecular Sciences, titled “Extracellular Vesicle Treatment Alleviates Neurodevelopmental and Neurodegenerative Pathology in Cortical Spheroid Model of Down Syndrome

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UMass Neurosciences Publications – Winter 2023

Benjamin Marlin

This month’s featured researcher in Benjamin Marlin. Ben is an Associate Professor in the Manning College of Information and Computer Science, where he directs the Robust and Efficient Machine Learning (REML) group. Their work is s research is informed by real-world applications including clinical and mobile health. He was an author on paper that was published in January in the Journal Translational Behavioral Medicine, which describes some of the efforts of the Intensive Longitudinal Health Behaviors Network (ILHBN) to harmonize data collection across many different studies and data streams. Ben is also and Associate Director of the Massachusetts AI & Technology Center for Connected Care in Aging & Alzheimer’s Disease (MassAITC), which fosters the development of artificial intelligence for technology that support healthy aging at home for older adults and individuals with Alzheimer’s disease.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in January and February. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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UMass Neurosciences Publications – December 2022

Gerald Downes

This month’s featured researcher is Dr. Gerald Downes, who is an Associate Professor in the Department of Biology. His lab uses zebrafish to understand how genes and neural networks in the brain and spinal cord control movement. They are also studying mechanisms that contribute to epilepsy with the hope of developing new therapeutics to treat these disorders. He and his PhD students are authors on a paper titled, “Amyotrophic Lateral Sclerosis-Associated Persistent Organic Pollutant cis-Chlordane Causes GABAA-Independent Toxicity to Motor Neurons, Providing Evidence toward an Environmental Component of Sporadic Amyotrophic Lateral Sclerosis“, which appeared this month in Chemical Neuroscience. This work was a collaboration with researchers at Wesleyan University.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in December. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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UMass Neurosciences Publications – November 2022

Dr. Agnès Lacreuse

This month’s featured research is Dr. Agnès Lacreuse. Agnès is a Professor in the Department Psychological & Brain Sciences. Her work is focused on age-related cognitive decline in a nonhuman primate with a short lifespan, the common marmoset (C. jacchus). Research from her lab recently appeared in the journal, Hormones and Behavior, showing that Letrozole, an aromatase inhibitor used in breast cancer treatment, alters gene expression in neurons of the hippocampus, a region of the brain involved with memory. The first author on this intriguing study was Melise Edwards, a PhD student in the Neuroscience and Behavior Graduate Program.

Here’s what else is new for ‘ ”University of Massachusetts” AND Amherst AND neuroscience’ in PubMed. These publications appeared online in November. They are just a fraction of the neuroscience research that occurs on campus. You can click on the PubMed ID to find the publication.

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