Dog Genes Summary

Genes

lettergenefull nametraits
EMC1Rmelanocortin 1 receptoreumelanin (requires signal molecule from agouti or defb) vs. pheomelanin
ee produces a non-functioning MC1R
Kdefb103defensin beta 103 (= CBD103 beta-defensin 103)dominant black has a glycine deletion
KB makes a signal that binds tightly to MC1R, preventing agouti expression
BTyRP1tyrosinase related protein 1black (B_) vs brown (bb)
AASIPAgouti Signaling ProteinASIP promotes pheomelanin (aa: no signal, A_ signal with varying on-off patterns)

MC1R Alleles

lettergenefull nametraits
E
ee

Agouti Alleles

lettergenefull nametraits
Ay
Aw
aa

NOTE: If you have the nucleotide sequence for an individual and the reference amino acid sequence, to compare them:
Blastx
Query: nucleotide sequence
Subject: reference amino acid sequence