“Mouse blastocyst outgrowth” by Xinjian (Dorris) He

Recent Publications

2024

Chander A, Mager J. Loss of KANSL3 leads to defective inner cell mass and early embryonic lethality. Mol Reprod Dev. 2024 May;91(5):e23760. doi: 10.1002/mrd.23760. PMID: 38769918.

He XD, Phillips S, Hioki K, Majhi PD, Babbitt C, Tremblay KD, Pobezinsky LA, Mager J. TATA-binding associated factors have distinct roles during early mammalian development. Dev Biol. 2024 Apr 7;511:53-62. doi: 10.1016/j.ydbio.2024.04.002.

Srinivasan S, He X, Mirza S, Mager J. Exosome complex components 1 and 2 are vital for early mammalian development. Gene Expr Patterns. 2024 Mar;51:119346. doi: 10.1016/j.gep.2023.119346

2023

Wang F, Chander A, Yoon Y, Welton JM, Wallingford MC, Espejo-Serrano C, Bustos F, Findlay GM, Mager J, Bach I. Roles of the Rlim-Rex1 axis during X chromosome inactivation in mice. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2313200120. doi: 10.1073/pnas.2313200120. Epub 2023 Dec 19. PMID: 38113263; PMCID: PMC10756295.

Wu X, Liu Y, Wang W, Crimmings K, Williams A, Mager J, Cui W. Early embryonic lethality of mice lacking POLD2. Mol Reprod Dev. 2023 Feb;90(2):98-108. doi: 10.1002/mrd.23663.

Mathew V, Mei A, Giwa H, Cheong A, Chander A, Zou A, Blanton RM, Kashpur O, Cui W, Slonim D, Mahmoud T, O’Tierney-Ginn P, Mager J, Draper I, Wallingford MC. hnRNPL expression dynamics in the embryo and placenta. Gene Expr Patterns. 2023 Jun;48:119319. doi: 10.1016/j.gep.2023.119319.

Jeon T, Makabenta JMV, Park J, Nabawy A, Cicek YA, Mirza SS, Welton J, Hassan MA, Huang R, Mager J, Rotello VM. Antimicrobial polymer-siRNA polyplexes as a dual-mode platform for the treatment of wound biofilm infections. Mater Horiz. 2023 Nov 27;10(12):5500-5507. doi: 10.1039/d3mh01108a.

Wang F, Chander A, Yoon Y, Welton JM, Wallingford MC, Espejo-Serrano C, Bustos F, Findlay GM, Mager J, Bach I. Roles of the Rlim-Rex1 axis during X chromosome inactivation in mice. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2313200120. doi: 10.1073/pnas.2313200120.

2022

Bell CJ, Gupta N, Tremblay KD, Mager J. Borcs6 is required for endo-lysosomal degradation during early development. Mol Reprod Dev. 2022 Aug;89(8):337-350. doi: 10.1002/mrd.23626.

2021

Su J, Miao X, Archambault D, Mager J, Cui W. ZC3H4-a novel Cys-Cys-Cys-His-type zinc finger protein-is essential for early embryogenesis in mice. Biol Reprod. 2021 Feb 11;104(2):325-335. doi: 10.1093/biolre/ioaa215. PMID: 33246328; PMCID: PMC7876667. 

Miao X, Sun T, Barletta H, Mager J, Cui W. Loss of RBBP4 results in defective inner cell mass, severe apoptosis, hyperacetylated histones and preimplantation lethality in mice. Biology of Reproduction. 2021;103(1): 13–23. doi:10.1093/biolre/ioaa046. 

2020

Miao X, Sun T, Golan M, Mager J, Cui W. Loss of POLR1D results in embryonic lethality prior to blastocyst formation in mice. Mol Reprod Dev. 2020 Nov;87(11):1152-1158. doi: 10.1002/mrd.23427. Epub 2020 Oct 6. PMID: 33022126; PMCID: PMC7686077.

Cheong A, Archambault D, Degani R, Iverson E, Tremblay KD, Mager J. Nuclear-encoded mitochondrial ribosomal proteins are required to initiate gastrulation. Development. 2020;147(10):dev188714. Published 2020 May 26. doi:10.1242/dev.188714

Archambault D, Cheong A, Iverson E, Tremblay KD, Mager J. Protein phosphatase 1 regulatory subunit 35 is required for ciliogenesis, notochord morphogenesis, and cell-cycle progression during murine development [published online ahead of print, 2020 Jul 3]. Dev Biol. 2020;S0012-1606(20)30186-X. doi:10.1016/j.ydbio.2020.06.011.

Cui W, Cheong A, Wang Y, et al. MCRS1 is essential for epiblast development during early mouse embryogenesis. Reproduction. 2020;159(1):1-13. doi:10.1530/REP-19-0334.

Tellier AP, Archambault D, Tremblay KD, Mager J. The elongation factor Elof1 is required for mammalian gastrulation. PLoS One. 2019;14(7):e0219410. Published 2019 Jul 5. doi:10.1371/journal.pone.0219410.

Cheong A, Degani R, Tremblay KD, Mager J. A null allele of Dnaaf2 displays embryonic lethality and mimics human ciliary dyskinesia. Hum Mol Genet. 2019;28(16):2775-2784. doi:10.1093/hmg/ddz106.

Cui W, Marcho C, Wang Y, et al. MED20 is essential for early embryogenesis and regulates NANOG expression. Reproduction. 2019;157(3):215-222. doi:10.1530/REP-18-0508.

Cui W, Mager J. Transcriptional Regulation and Genes Involved in First Lineage Specification During Preimplantation Development. Adv Anat Embryol Cell Biol. 2018;229:31-46. doi:10.1007/978-3-319-63187-5_4.

Full bibliography from Mager Lab here.