, RNA modifications and their role in regulating KSHV replication and pathogenic mechanisms. Accepted at in Journal of Medical Virology 2024.
, , , The antiviral protein Shiftless blocks p-body formation during KSHV infection. BioRxiv 2024 10.1101/2023.11.16.567185.
Bermudez Y., Hatfield D., Muller M. A Balancing Act: the viral-host battle over RBPs. Viruses 2024, 16, 474. https://www.mdpi.com/1999-4915/16/3/474
Muller M. Viral manipulation of host cell gene expression. Seminars in Cell and Developmental Biology. 2023 146.1–1. Editorial and Front Cover.
Bermudez Y, Miles J, Muller M. Nonstructural protein 1 (nsp1) widespread RNA decay phenotype varies among coronaviruses. iScience. 2023 Jan 20; 26(1): 105887. https://www.sciencedirect.com/science/article/pii/S2589004222021605
, , Hatfield D. Shiftless Restricts Viral Gene Expression and Influences RNA Granule Formation during KSHV lytic replication. J Virol 2022 https://journals.asm.org/doi/10.1128/jvi.01469-22
Rodriguez W, Muller M. Shiftless, A Critical Piece of the Innate Immune Response to Viral Infection. Viruses 2022, 14(6), 1338. https://www.mdpi.com/1999-4915/14/6/1338
Macveigh-Fierro D., Cicerchia A., Cadorette A., Sharma V., Muller M. The m6A reader YTHDC2 is essential for escape from KSHV SOX-induced RNA decay.
Hoffman D, Rodriguez W, Macveigh-Fierro D, Miles J, Muller M. The KSHV ORF20 Protein Interacts With The Viral Processivity Factor ORF59 And Promotes Viral Reactivation. Microbiol Spectr 2021 9:e00145-21. https://journals.asm.org/doi/10.1128/Spectrum.00145-21
Macveigh-Fierro D, Rodriguez W, Miles J, Muller M. Stealing the Show: KSHV Hijacks Host RNA Regulatory Pathways to Promote Infection. Viruses 2020, 12, 1024. https://www.mdpi.com/1999-4915/12/9/1024
Rodriguez W, Macveigh-Fierro D, Miles J, Muller M. Fated for decay: RNA elements targeted by viral endonucleases. Seminars in Cell and Developmental Biology, 2020. https://www.sciencedirect.com/science/article/abs/pii/S1084952119302009?via%3Dihub
Rodriguez W, Srivastav A, Muller M. C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi Sarcoma Associated Herpesvirus (KSHV). J Virol 2019, 93:e00373. https://jvi.asm.org/content/early/2019/03/28/JVI.00373-19
Muller M, Glaunsinger B. Nuclease escape elements protect messenger RNA against cleavage by multiple viral endonucleases. PLoS Pathogens 2017, 13(8): e1006593. http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006593
Muller M, Hutin S, Marigold O, Li KH, Burlingame A, Glaunsinger B. A Ribonucleoprotein Complex Protects the Interleukin-6 mRNA from Degradation by Distinct Herpesviral Endonucleases. PLoS Pathogens 2015, 11(5): e1004899.http://journals.plos.org/ plospathogens/article?id=10.1371/journal.ppat.1004899
Muller M, Demeret C. CCHCR1 Interacts Specifically with the E2 Protein of Human Papillomavirus Type 16 on a Surface Overlapping BRD4 Binding. PLoS ONE 2014, 9(3): e92581.(Highlighted in Faculty of 1000: F1000Prime.com/718323275# eval793493753). http://journals.plos.org/plosone/article?id=10.1371/journal.pone.009258 1
Muller M, Cassonnet P, Favre M, Jacob Y & Demeret C. A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions. J. Vis. Exp. 2013, (77), e50404.https://www.jove.com/video/50404/a-comparative-approach-to-characterize-landscape-host-pathogen
Muller M, & Demeret C. The HPV E2-host protein-protein interactions: a complex cellular network hijacking. Open J. Virol 2012, 6,173-189. https://www.ncbi. nlm.nih.gov/pmc/articles/PMC3547520/
Neveu G., Cassonnet P., Vidalain P.O., Rolloy C., Mendoza J., Jones L., Tangy F., Muller M., Demeret C., Tafforeau L., Lotteau V., Rabourdin-Combe C., Travé G., Dricot A., Hill D., Vidal M., Favre M., Jacob Y. Comparative analysis of virus-host interactomes with HT-GPCA, a high-throughput mammalian assay to probe protein interactions. Methods 2012, 58, 349–359. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546263/
Muller M, Jacob Y, Jones L, Weiss A, Brino L, Chantier T , Lotteau V, Favre M., Demeret C. Large Scale Genotype Comparison of Human Papillomavirus E2-Host Interaction Networks Provides New Insights for E2 Molecular Functions. PLoS Pathogens 2012, 8(6): e1002761. (Comment in: Pathogens and Global Health: Pathog Glob Health. 2012 Jul;106(3):141). http://journals.plos.org/plospathogens/articleid=10.1371/journal.ppat.100 2761
Cassonnet P, Rolloy C, Neveu G, Vidalain PO, Chantier T, Pellet J, Jones L, Muller M, Demeret C, Gaud G, Vuillier F, Lotteau V, Tangy F, Favre M, Jacob Y. Benchmarking of a luciferase-based assay for detecting protein-protein interactions. Nature Methods 2011, 8 (990–992). http://www.nature.com/nmeth/journal/v8/n12/abs/nmeth.1773.html