Lisa Baumoel

A new research progress from our lab was just published in FEMS Microbiology Letters. The article, currently available as the accepted manuscript, is entitled “Deletion of PimE mannosyltransferase results in increased copper sensitivity in Mycobacterium smegmatis”.

In this study, we discovered that the high concentration of copper present in Middlebrook 7H10 medium, a standard agar-based growth medium for mycobacteria research, is actually toxic to the pimE gene deletion mutant. We attributed this defect to the defective permeability barrier function of the mutant’s cell envelope.

Bill Eagen

This work was led by two first authors Bill Eagen and Lisa Baumoel. Bill is a current senior undergraduate. Lisa was an undergraduate researcher, who continued in my lab to complete the fifth-year accelerated Master’s program.

Congratulations to Bill and Lisa!

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